Concentration of hsp60, hsp70, anti-hsp60, and anti-hsp70 in serum from non-diabetic, mild diabetic, and severe diabetic rats. Sera from rats without diabetes (ND), mild diabetes (MD), and severe diabetes (SD) were tested for hsp60 (a), anti-hsp60 (b), hsp70 (c), and anti-hsp70 (d) by ELISA. Data are presented as mean ± standard deviation. *P < 0.05, compared to ND; #P < 0.05, compared to MD