Fig. 1.

Neuron morphology and density in SO and OBX mice. (a) Representative photomicrographs of frontal sections through the hippocampus and temporal cortices of untreated control SO mice (1, 2, 3) and OBX mice (4, 5, 6). CT temporal cortex, CA1 and CA3 areas of hippocampus. Different pathological states of neurons such as pyknosis (P), karyolysis (K), cytolysis (C), or vacuolization (V) are indicated by arrows. (b) Neuronal density in CA1 and CA3 areas of hippocampus. SO sham-operated, OBE bulbectomized mice. Measurements performed 1.5 month after the surgery. Asterisks indicate significant differences ***p < 0.001 relative to the SO group. a (×20 and × 40)