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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Dev Biol. 2012 Oct 24;373(1):95–106. doi: 10.1016/j.ydbio.2012.10.007

Fig. 8. GATA-3, required for luminal identity, is reduced in Twsg1−/− MGs.

Fig. 8

GATA-3 expression is reduced in Twsg1−/− MGs. ECAD was used to mark luminal epithelial cells and most ECAD positive cells in the WT TEB express GATA-3 (A–D) and mature duct (I–L) while the Twsg1−/− TEB (E–H) and mature duct (I–L) consist of a mosaic of GATA-3 positive and GATA-3 negative luminal cells. Most cells shed into the lumen are GATA-3 negative (P). All images were taken at 40X. Boxes in C, G, K, and O correspond to the magnified images in D, H, L, and P, respectively.