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F9 cells are more resistant to Dkk1 inhibition of the Wnt/β-catenin signaling pathway than F9 Cripto-1-/- cells. (A) SuperTOPFLASH assay in F9 and F9 Cripto-1-/- cells treated with rhWnt3a (100 ng/ml) alone or in combination with different concentration of rmDkk1. (B) Dkk1 mRNA expression in F9 and F9 Cripto-1-/- cells as assessed by RT-PCR.
