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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Neuromolecular Med. 2012 Jul 12;14(4):328–337. doi: 10.1007/s12017-012-8190-1

Figure 1. Comparison of the gating properties of the WT CLC-1 and the point mutant G233S.

Figure 1

(A) Voltage protocols used to evaluate the overall open probability (Po) of the channel (left) and the common-gate open probability (Poc, right), respectively. (B and C) Original recording traces of the WT (B) and G233S mutant (C) CLC-1 in responses to both voltage protocols.