Figure 6.
PACT of the cortical responses to forepaw stimulations. (a-b) Relative changes of the PA amplitudes (shown in color) acquired at (a) 2-NBDG-dominant 478 nm and (b) hemoglobin-dominant 570 nm under the right paw stimulation (RPS) and left paw stimulation (LPS), superimposed on the resting-state image (shown in gray). The threshold for the overlay transparency was set to be 10% of the maximum response. (c) Overlaid images showing the relative changes of 2-NBDG concentration (C2-NBDG, shown in blue) and total hemoglobin concentration (CHb, shown in red), superimposed on the resting-state image at 570 nm (shown in gray). (d) Relative changes of C2-NBDG and CHb averaged over three mice. Error bars: standard deviation. The p values were calculated from paired Student’s t-test between stimulated states P2 or P4 and resting states P1 or P3.