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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Pediatr Clin North Am. 2012 Oct 18;60(1):189–207. doi: 10.1016/j.pcl.2012.09.008

Table 1.

Nutrient content of commonly used human milk fortifiers in North America

Enfamil®
Human Milk
Fortifier
Acidified
Liquid (4
vials = 20
ml) Add to
100 ml EBM
Similac®
Special
Care® 30
cal/oz (50
ml) Add to
50 ml EBM
Prolact +4
H2MF™ (20
ml)* Add to
80 ml EBM
Similac®
Human
Milk
Fortifier (4
packets =
3.6 g) Add
to 100 ml
EBM
Enfamil®
Human
Milk
Fortifier (4
packets =
2.8 g) Add
to 100 ml
EBM)
Formulation Liquid Powder
Protein source Bovine Human Bovine
Calories 30 50 28 14 14
Protein (g) 2.2 1.5 1.2 1.0 1.1
Fat (g) 2.3 3.3 1.8 0.36 1
Carbohydrate (g) <1.2 3.9 1.8 1.8 <0.4
Vitamin A (IU) 1160 625 61 620 950
Vitamin D (IU) 188 75 26 120 150
Vitamin E (IU) 5.6 2.0 0.4 3.2 4.6
Vitamin K (meg) 5.7 6.0 <0.2 8.3 4.4
Vitamin B1 (meg) 184 125 4 233 150
Vitamin B2 (meg) 260 310 15 417 220
Vitamin B6 (meg) 140 125 4.1 211 115
Vitamin B12 (meg) 0.64 0.27 0.05 0.64 0.18
Niacin (meg) 3700 2500 52.4 3570 3000
Folic Acid (meg) 31 18.5 5.4 23 25
Pantothenic acid (meg) 920 950 74.8 1500 730
Biotin (meg) 3.4 18.5 Not Available 26 2.7
Vitamin C (mg) 15.2 18.5 <0.2 25 12
Calcium (mg) 116 90 103 117 90
Phosphorus (mg) 63 50 53.8 67 50
Iron (mg) 1.76 0.9 0.1 0.35 1.44
Zinc (mg) 0.96 0.75 0.7 1.0 0.72
Copper (mcg) 60 125 64 170 44
Manganese (meg) 10 6 <12 7.2 10
Sodium (mg) 27 22 37 15 16
Potassium (mg) 45 65 50 63 29
Chloride (mg) 28 41 29 38 13
*

values are averages and may vary.