Supine transverse 2D CTC image (A) with polyp window setting (2000/0) shows a 10-mm sessile polyp in the cecum (calipers). On a soft tissue window setting (B, 350/40), the polyp appears to decrease in size to less than 10-mm. Polyp measurement on soft tissue windows could lead to inappropriate management. On the prone 2D CTC images (C and D), the polyp (arrow) is submerged under densely opacified fluid, which further decreases the apparent polyp size. Note how the lesion is barely perceptible on the soft tissue window setting (D).
(From reference 5, with permission)