Table 2.
Distributions of plasma levels of biomarkers among cases with colorectal adenoma and polyp-free controls
| Biomarkers (pg/ml) | Cases (n = 158) | Controls (n = 203) | P* |
|---|---|---|---|
| Median (intertertile range) | Median (intertile range) | ||
| sRAGE | 42.3 (25.5-102.2) | 49.7 (27.2-100.5) | 0.26 |
| sTNFRI | 1437 (899-2117) | 1297 (859-2021) | 0.26 |
| sTNFRII | 6352 (4445-8951) | 6456 (4349-9201) | 0.89 |
| sIL6R | 19036 (12705-29157) | 18489 (12853-27574) | 0.60 |
| EGF | 109 (48-277) | 104 (41-219) | 0.15 |
| MCP1 | 405 (263-523) | 400 (269-528) | 0.95 |
| VEGF† | 69.3 (33.1-161) | 52.4 (28.4-138) | 0.06 |
Abbreviations: epidermal growth factor (EGF), monocyte chemotactic protein-1 (MCP1), soluble interleukin-6 receptor (sIL-6R), soluble receptor for advanced glycation end-products (sRAGE), soluble tumor necrosis factor receptor I (sTNFRI), soluble tumor necrosis factor receptor II (sTNFRII), vascular endothelial growth factor (VEGF).
*
P value for Mann-Whitney U test.
†
Calculated from the values above the detection limit.