Table 2.
FDR adjusted P-value in global testing
| # SNPs | Remaining | SNP | ReliefF | P-values of global testing | |||||
|---|---|---|---|---|---|---|---|---|---|
| Removed |
SNP (GxG) |
Removed |
Score |
KS |
Inverse chi |
Inversenorm |
Logit |
Wilcoxon |
Tippett |
| 0 |
25(300) |
|
|
0.29121 |
0.22008 |
1.00000 |
1.00000 |
0.80991 |
0.33927 |
| 1 |
24(276) |
rs35252139 |
−0.0308 |
0.21644 |
0.12424 |
1.00000 |
1.00000 |
0.55397 |
0.33340 |
| 2 |
23(253) |
rs35229708 |
−0.0308 |
0.16697 |
0.06603 |
1.00000 |
1.00000 |
0.43198 |
0.32718 |
| 3 |
22(231) |
rs2298383 |
−0.0279 |
0.13417 |
0.03087 |
1.00000 |
1.00000 |
0.25182 |
0.32062 |
| 4 |
21(210) |
rs12995526 |
−0.0250 |
0.16987 |
0.05667 |
1.00000 |
1.00000 |
0.45717 |
0.31374 |
| 5 |
20(190) |
rs7699188 |
−0.0202 |
0.11033 |
0.01793 |
1.00000 |
1.00000 |
0.31680 |
0.30658 |
| 6 |
19(171) |
rs1805087 |
−0.0183 |
0.03887 |
0.00320 |
1.00000 |
1.00000 |
0.18665 |
0.29916 |
| 7 |
18(153) |
rs4149056 |
−0.0067 |
0.02048 |
0.00106 |
1.00000 |
1.00000 |
0.09019 |
0.29154 |
| 8 |
17(136) |
55930652 |
−0.0038 |
0.01051 |
0.00080 |
1.00000 |
1.00000 |
0.10254 |
0.28376 |
| 9 |
16(120) |
* no rs [35] |
−0.0029 |
0.00455 |
0.00016 |
1.00000 |
1.00000 |
0.02642 |
0.27592 |
| 10 |
15(105) |
rs17803441 |
0.0010 |
0.00312 |
0.00011 |
1.00000 |
1.00000 |
0.00567 |
0.26811 |
| 11 |
14(91) |
rs34743033 |
0.0087 |
0.00022 |
0.00001 |
1.00000 |
1.00000 |
0.00015 |
0.26049 |
| 12 |
13(78) |
rs61886492 |
0.0096 |
0.00022 |
0.00000 |
0.00001 |
0.00000 |
0.00006 |
0.25328 |
| 13 |
12(66) |
rs71391718 |
0.0183 |
0.00008 |
0.00000 |
0.00000 |
0.00000 |
0.00001 |
0.25328 |
| 14 |
11(55) |
rs3758149 |
0.0192 |
0.00008 |
0.00000 |
0.00000 |
0.00000 |
0.00006 |
0.25328 |
| 15 |
10(45) |
rs1801131 |
0.0240 |
0.00026 |
0.00004 |
0.00004 |
0.00004 |
0.00016 |
0.25328 |
| 16 |
9(36) |
rs1801394 |
0.0365 |
0.00022 |
0.00004 |
0.00003 |
0.00003 |
0.00015 |
0.25328 |
| 17 |
8(28) |
rs8788 |
0.0375 |
0.00008 |
0.00003 |
0.00002 |
0.00002 |
0.00015 |
0.25328 |
| 18 |
7(21) |
rs7387 |
0.0452 |
0.01051 |
0.00255 |
0.00547 |
0.00442 |
0.00799 |
0.25328 |
| 19 |
6(15) |
rs1801133 |
0.0481 |
0.05212 |
0.06679 |
0.10791 |
0.12185 |
0.05337 |
0.25328 |
| 20 |
5(10) |
rs8971 |
0.0481 |
|
|
|
|
|
|
| 21 |
4(6) |
rs2274976 |
0.0644 |
|
|
|
|
|
|
| 22 |
3(3) |
rs1979277 |
0.0673 |
|
|
|
|
|
|
| 23 |
2(1) |
rs11280056 |
0.0702 |
|
|
|
|
|
|
| 24 |
|
rs3733890 |
0.0750 |
|
|
|
|
|
|
| 25 |
|
rs3733890 |
0.1163 |
|
|
|
|
|
|
| Optimal number of SNPs removed | 5 | 4 | 11 | 11 | 8 | Not Found | |||