Table 1.

Completed, ongoing and planned microbicide ring clinical studies

Study	Description	Phase	Countries	Number women	Status
IPM 001	Dapivirine ring safety	I	Belgium	12	Completed
IPM 008	Dapivirine ring safety	I	Belgium	13	Completed
IPM 011	Placebo ring safety and acceptability	n/a	South Africa/Tanzania	170	Completed
IPM 013	Dapivirine ring PK	I	Belgium	48	Completed
IPM 015	Dapivirine ring safety	I/II	Kenya, Malawi, South Africa, Tanzania	280	Data analysis
IPM 018	Dapivirine ring PK	I	Belgium	24	Completed
IPM 024	Dapivirine ring PK	I	Belgium	16	Completed
IPM 026/ MTN 013	Maraviroc, dapivirine, and dapivirine-maraviroc combination ring	I	USA	48	Ongoing in 2012
IPM 027	Dapivirine ring long-term safety	II	South Africa, Rwanda, Kenya, Malawi	1650	Ongoing in 2012
MTN 020	Dapivirine ring efficacy and safety	III	Malawi, South Africa, Uganda, Zambia, Zimbabwe	3475	Ongoing in 2012

Notes: IPM refers to clinical studies completed or being undertaken by the International Partnership for Microbicides (Silver Spring, MD). MTN refers to studies being undertaken by the Microbicide Trails Network, a US National Institutes of Health-funded worldwide collaborative clinical trials network focused on preventing the sexual transmission of HIV.

Abbreviations: MRI, magnetic resonance imaging; PII, Phase II; C, control.