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Fever responses in rats with lesions in the PVH (gray diamonds), dSPZ (black squares), or controls (gray triangles) after intravenous LPS injection. The PVH lesion significantly attenuated fever (66.6%; p < 0.01) compared with the controls. In contrast, the rats with dSPZ lesions showed fever responses that did not differ significantly from the controls (p > 0.05). The injection time is at zero on the x-axis.
