Fig. 2.

Photomicrographs showing lesions (outlined bylight dashed line) in the ventral SPZ (A–C, vSPZ), dorsal SPZ (D–F, dSPZ), and PVH (G–I). Lesions of the vSPZ typically spared the SCN as confirmed by immunostaining for VIP and AVP (A–C). Lesions of the dSPZ (D) did not affect the PVH, as shown by immunostaining for Fos (E, induced by LPS) and AVP (F). Lesions of the PVH (G, PVH border outlined in heavy dashed line) were verified by loss of Fos-ir neurons after LPS injection and by loss of AVP-ir neurons (H, I).