Figure 3.
FcRn-sufficient neonatal mice absorbed allergen-specific IgE when fed as IgG1 anti-IgE/IgE immune complexes. (A) Western blot analysis of antibody mixtures confirming the formation of immune complexes. Molecular weight markers are in kDa. (B) Neonatal mice fed IgG1 anti-IgE/IgE immune complexes absorbed TNP-specific IgE systemically. (C) Neonatal mice injected with IgG1 anti-IgE/IgE immune complexes or IgE alone absorbed TNP-specific IgE systemically. The number of mice in each group is included. * P < 0.05, ** P ≤ 0.01.