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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Clin Exp Allergy. 2012 Dec;42(12):1791–1800. doi: 10.1111/j.1365-2222.2012.04043.x

Figure 5.

Figure 5

Serum obtained from neonatal mice previously fed IgG1 anti-IgE (B1E3)/IgE immune complexes passively sensitized RBL cells. RBL cells on the same plate were preincubated with control IgE or serum obtained from 3 neonatal mice per group. Degranulation was induced by the addition of TNP-OVA. RBL cells preincubated with serum obtained from neonatal mice fed IgG1 anti-IgE (B1E3)/IgE immune complexes released significantly greater amounts of β-hexosaminidase than those preincubated with serum obtained from neonatal mice fed isotype control and IgE, or IgG1 anti-IgE (B1E3) alone. *** P < 0.001. Similar results were obtained in one additional experiment.