Figure 1. The rate of recovery from inactivation is unaffected by lidocaine. Channels were held at holding potential of -120 mV and activated by 750 ms of depolarizing pulses to -20 mV every 20 sec. (A) A representative family of current traces of WT NaChBac, showing the step-wise recovery from inactivation. Scale bar represents 1 sec and 2 nA. (B) Normalized peak currents are plotted as a function of recovery time interval. The rate of recovery from inactivation is significantly increased in the presence of 1 mM benzocaine, where asterisks indicate (p < 0.05).