Table 3.
Final set of derived proteins representing candidate biomarker of AD
| STANDARD PROTEIN SYMBOL | COMMON ALIASES | |
|---|---|---|
| Alpha 1-antichymotrypsin |
SERPINA3 |
serpin peptidase inhibitor clade A, AACT, ACT |
| Amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease amyloid protein) |
APP |
AD1 (Alzheimer disease), ABETA (amyloid beta A4 protein) |
| Apolipoprotein D |
APOD |
|
| Apolipoprotein E |
apoE |
AD2 (Alzheimer disease 2) |
| B-cell leukemia/lymphoma 2 |
BCL2 |
|
| Beta-site APP-Cleaving Enzyme 1 |
BACE1 |
|
| Butyrylcholinesterase |
BCHE |
|
| C-reactive protein, pentraxin-related |
CRP |
|
| Choline Acetyltransferase |
CHAT |
CHOACTase |
| Clusterin |
CLU |
APOJ (Apolipoprotein J) |
| Complement component 1, q subcomponent, beta polypeptide |
C1QB |
|
| Estrogen Receptor 1 (alpha) |
ESR1 |
|
| Glial fibrillary acidic protein |
GFAP |
|
| Heat shock 70kD protein 5 (glucose-regulated protein) |
HSPA5 |
|
| Interleukin 1 beta |
IL1B |
|
| Interleukin 6 |
IL6 |
IFNB2 (Interferon beta-2) |
| Matrix Metallopeptidase 9 |
MMP9 |
CLG4B (92 kDa gelatinase, 92 kDa type IV collagenase) |
| Nerve Growth Factor |
NGF |
NGFB |
| Nitric Oxide Synthase 2A |
NOS2 |
NOS2A, INOS (Inducible NOS), HEP-NOS (Hepatocyte NOS) |
| PRKC, apoptosis, WT1, regulator |
PAWR |
PAR4 (Prostate apoptosis response 4 protein) |
| Prostaglandin-Endoperoxide Synthase 2 |
PTGS2 |
PGHS2, COX2 (Cyclooxygenase 2b) |
| Transforming Growth Factor, Beta 1 |
TGFB1 |
|
| Transthyretin |
TTR |
|
| Tumor Necrosis Factor (TNF superfamily, member 2) |
TNF |
TNFA, TNF-alfa |
| Urokinase Plasminogen Activator Receptor | PLAUR | uPAR |