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. 2012 Dec;26(12):4821–4826. doi: 10.1096/fj.12-210872

Figure 1.

Figure 1.

Developmental programs affecting aging. Hypothetical developmental processes that result in a given molecular, cellular, or physiological change with biological time contribute to increase or optimize function during the reproductive period. The hypothesis advocated in this work is that these processes, whose trajectories are set during development, continue after maturity and contribute to dysfunction later in life.