Figure 2. ApoE3 binds LPS with greater affinity than apoE4.

LPS-coated wells were incubated with increasing concentrations of apoE3 or apoE4 alone (A) or complexed to DMPC (B). LPS-bound apoE was detected using an apoE antibody with secondary HRP, with adhesion directly proportional to absorbance (n = 6). Dashed line, DMPC background. *P<0.01.