Table 3.
Self-Reported Prenatal Tobacco Smoke Category | N† | Birth, N=293 (SD) [95% CI] | 4-Week, N=297 (SD) [95% CI] | 1 Year, N=266 (SD) [95% CI] | 2 Year, N=229 (SD) [95% CI] | 3 Years, N=202 (SD) [95% CI] |
---|---|---|---|---|---|---|
Mean among unexposed | 214 | 13.0 (1.5) | 14.7 (1.4) | 16.9 (1.6) | 16.6 (1.3) | 15.9 (1.3) |
SHS | 43 | 0.0 [−0.4, 0.5] | 0.0 [−0.4, 0.4] | −0.1 [−0.7, 0.4] | −0.1 [−0.6, 0.5] | 0.0 [−0.5, 0.6] |
Active | 36 | 0.3 [−0.2, 0.8] | 0.3 [−0.2, 0.8] | 0.2 [−0.4, 0.8] | 0.6 [0.0, 1.2] | 1.1 [0.4, 1.7] |
| ||||||
Categorical Prenatal Serum Cotinine Concentrations | N† | Birth, N=300 (SD) [95% CI] | 4-Week, N=303 (SD) [95% CI] | 1 Year, N=273 (SD) [95% CI] | 2 Years, N=236 (SD) [95% CI] | 3 Years, N=209 (SD) [95% CI] |
Mean among unexposed (<0.015 ng/mL) | 116 | 13.2 (1.4) | 14.9 (1.3) | 17.0 (1.7) | 16.4 (1.2) | 15.7 (1.2) |
SHS (0.015–3 ng/mL) | 153 | −0.2 [−0.5, 0.2] | −0.2 [−0.5, 0.1] | −0.1 [−0.6, 0.3] | 0.3 [−0.1, 0.7] | 0.4 [0, 0.8] |
Active (>3 ng/mL) | 31 | 0.0 [−0.6, 0.6] | 0.1 [−0.5, 0.6] | 0.4 [−0.4, 1.1] | 0.6 [−0.1, 1.4] | 1.0 [0.3, 1.8] |
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Continuous Prenatal Serum Cotinine Concentrations | ||||||
Log10-transformed mean cotinine | 300 | 0.0 [−0.2, 0.2] | 0.0 [−0.2, 0.2] | 0.1 [−0.1, 0.3] | 0.2 [0.0, 0.4] | 0.3 [0.1, 0.5] |
Log10-transformed mean cotinine (SHS exposed only)‡ | 269 | −0.1 [−0.4, 0.2] | −0.2 [−0.5, 0.1] | −0.2 [−0.6, 0.2] | 0.2 [−0.2, 0.5] | 0.3 [−0.1, 0.6] |
-Adjusted for child age (in years), child age squared, child age cubed, maternal age (<25, 25–34, and >34 years), education (<12, 12, and >12 years), race (non-Hispanic white, non-Hispanic black, and other), marital status (married and non-married), depression at baseline home visit (moderately or severely depressed and mildly or minimally depressed), breast feeding duration since last visit (years), parity (0, 1, and >1), income ($10,000 increments), and maternal BMI (kg/m2) at 16 weeks gestation.
-Sample size at birth
-Women could not have cotinine concentration > 3 ng/mL in any serum measurement. SHS-Secondhand smoke