Table 1.
AMH Low (n = 22) | AMH Mid (n = 22) | AMH High (n = 22) | p | |
---|---|---|---|---|
Iliac Artery Plaque Area (mm2) | ||||
Post-Treatment | 0.76 ± 0.12 | 0.46 ± 0.1 | 0.34 ± 0.08 | 0.02 |
AMH (ng/ml) | ||||
Baseline Tertile Mean | 4.94 ± 1.4 | 10.59 ± 1.3 | 21.3 ± 1.3 | 0.001 |
Tertile Range | 0.96–7.6 | 7.71 – 14.4 | 14.6 – 50.6 | NA |
Estradiol (pg/ml) | ||||
Baseline | 20.1 ± 5.3 | 21.6 ± 5.5 | 31.6 ± 5.3 | 0.3 |
Body weight (kg) | ||||
Baseline | 3.2 ± 0.1 | 3.1 ± 0.1 | 3.1 ± 0.1 | 0.86 |
Post-Treatment | 3.36 ± 0.2 | 3.31 ± 0.2 | 3.36 ± 0.2 | 0.97 |
TPC (mg/dl) | ||||
Baseline | 245.1 ± 11 | 237.2 ± 13 | 235.2 ± 11 | 0.82 |
Post-Treatment | 327.9 ± 16 | 290.9 ± 15 | 297.5 ± 17 | 0.23 |
HDLC (mg/dl) | ||||
Baseline | 44.2 ± 3 | 45.8 ± 3 | 42.8 ± 3 | 0.8 |
Post-Treatment | 44.7 ± 4 | 46.9 ± 4 | 43.3 ± 4 | 0.86 |
LDLC + VLDLC (mg/dl) | ||||
Baseline | 199.5 ± 14 | 191.4 ± 13 | 192.5 ± 13 | 0.9 |
Post-Treatment | 283.2 ± 18 | 244 ± 17 | 254.2 ± 19 | 0.3 |
TPC: HDLC | ||||
Baseline | 6.2 ± 0.6 | 6.1 ± 0.6 | 6.0 ± 0.6 | 0.5 |
Post-Treatment | 8.4 ± 0.7 | 7.4 ± 0.8 | 7.6 ± 0.8 | 0.56 |
LDLC + VLDLC: HDCL | ||||
Baseline | 5.2 ± 0.6 | 5.1 ± 0.6 | 5.0 ± 0.6 | 1 |
Post-Treatment | 7.4 ± 0.7 | 6.4 ± 0.7 | 6.6 ± 0.8 | 0.6 |
Baseline and 26 months post-diet measures of atherosclerosis, hormone and risk variable data are presented according to baseline (pre-treatment group assignment) tertiles of plasma AMH for all monkeys. Data are Mean ±SE.