TABLE 3.
Cardiometabolic Function
PCOS Subjects (n=28) |
Female Controls (n=28) |
Male Controls (n=28) |
P value ANOVA) |
|
---|---|---|---|---|
1MetS (n) (%) | 10 (35.7%) | 4 (14.3%) | 5 (17.6%) | 0.1 |
Fasting Glucose (mg/dl) | 96.6 ± 20.1 | 85.3 ± 13.5 | 94.6 ± 13.1 | 0.02 |
Fasting Insulin (IU) | 30.1 ± 18.5 | 20.4 ± 6.8 | 21.3 ± 12.8 | 0.03 |
2HOMA-IR >4 | 71.4%* (20/28) | 41.0% (9/22) | 34.8% (8/23) | <0.05 |
Fasting TG (mg/dl) | 125.5 ± 73.1 | 91.4 ± 38.9 | 110.4 ± 44.7 | 0.08 |
Fasting HDL (mg/dl) | 43.0 ± 10.9** | 50.5 ± 13.8 | 38.3 ± 7.1 | 0.001 |
Systolic blood pressure (mmHg) | 122.9 ± 13.6 | 117.1 ± 9.6 | 128.5 ± 11.5 | 0.002 |
Diastolic blood pressure (mmHg) | 69.8 ±11.2 | 66.4 ± 8.4 | 66.4 ± 8.1 | 0.3 |
Data represented as mean ± SD
Bonferroni adjustment:
p=0.04 compared to female control group, p=0.01 compared to male control group
p<0.05 compared to female controls p=0.4 compared to male control group
MetS; metabolic syndrome based on Weiss criteria(21)
HOMA-IR; fasting glucose (mg/dL) × fasting insulin (μU/mL)/405.