TABLE 4.
Polycystic Ovary Syndrome Sub-analysis
| PCOS with OSA (n=16) |
PCOS without OSA (n=12) |
P value | |
|---|---|---|---|
| Age (yrs) | 16.8 ± 2.1 | 16.6 ± 1.7 | 0.8 |
| 1BMI Z-score | 2.5 ± 0.3 | 2.3 ± 0.5 | 0.1 |
| Metformin (n) (%) | 5 (31.3%) | 5 (41.6%) | 0.6 |
| Oral contraceptives (n) (%) | 3 (18.8%) | 3 (25%) | 0.7 |
| Adenotonsillectomy (n) (%) | 6 (37.5%) | 3 (25%) | 0.5 |
| Free testosterone (pg/ml) | 9.7 ± 4.2 | 7.6 ± 4.5 | 0.3 |
| Total testosterone (ng/dl) | 54.2 ± 30.1 | 51.0 ± 23.3 | 0.2 |
| 2MetS (n) (%) | 9 (56.3%) | 1 (8.3%) | 0.03 |
| 3HOMA-IR>4 | 13(81.3 %) | 5 (41.6%) | 0.03 |
| Fasting glucose (mg/dl) | 99.3 ± 21.3 | 88.2 ± 8.9 | 0.07 |
| Fasting insulin (IU) | 8.4 ± 5.5 | 5.3 ± 3.6 | 0.09 |
| Fasting TG (mg/dl) | 149.7 ± 87.7 | 93.3 ± 25.8 | 0.03 |
| Fasting HDL (mg/dl) | 38.6 ± 8.7 | 49 ± 10.9 | 0.01 |
| Systolic blood pressure (mmHg) | 128.4 ± 12.8 | 115.6 ± 11.4 | 0.009 |
| Diastolic blood pressure (mmHg) | 71.4 ± 0.4 | 67.8 ± 11.5 | 0.4 |
Data represented as mean ± SD
1
Body mass index Z-score
2
MetS; metabolic syndrome based on Weiss criteria (21)
3
HOMA-IR; fasting glucose (mg/dL) × fasting insulin (μU/mL)/405