Mean ± SE cumulative food intake expressed as the number of pellets eaten after 48-h food deprivation with 0 μg (n = 7), 10-μg (n = 7), 40-μg (n = 7), and 80-μg doses (n = 7) of peripheral leptin for hamsters without a foraging requirement and a stationary wheel (Blocked Wheel group; top), hamsters with no foraging requirement and a freely moving wheel (Free Wheel group; middle), and hamsters with a foraging requirement (10 Revolutions/Pellet group; bottom) *P < 0.05 compared with the food-deprived group with 0 μg leptin control condition.