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. 2012 May 26;27(12):1587–1593. doi: 10.1007/s11606-012-2096-3

Table 3.

Percent of Patients Double-Dipping on Acetaminophen-Containing Medicines

Base Product % Indicating it is Safe to Take Max Dose of Base Product + Second Acetaminophen Product (below) P Value
Generic Arthritis Pain Reliever (1300 mg/dose) Brand Name PM Pain Reliever (1000 mg/dose) Brand Name Combination Pain Reliever (500 mg/dose) Brand Name Combination Cold & Cough (650 mg/dose)
Brand Name Pain Reliever (500 mg per gelcap; 2 every 4–6 hours) 11.6 21.7 11.0 20.1 <0.0001
Brand Name Combination Sinus Congestion & Pain Reliever (325 mg per caplet; 2 every 4 hours) 12.6 21.3 11.5 12.1 <0.0001