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. Author manuscript; available in PMC: 2012 Nov 29.
Published in final edited form as: Comp Biochem Physiol C Comp Pharmacol Toxicol. 1984;77(1):13–21. doi: 10.1016/0742-8413(84)90124-5

Fig. 6.

Fig. 6

Attenuation of 5-HT induced PAD by high levels of Mn2+. (A–C) Illustrates 5-HT responses recorded from a sucrose gapped hemisected spinal cord. In (A) the 1 µM TTX resistant 5-HT depolarization is shown. The superfusate was then switched to a solution containing 4 mM MnCl2, with no added TTX, and the 5-HT response again tested after 60 min exposure as shown in (B). Next the composition of the superfusate was returned to the original TTX containing solution and 5-HT once again tested 60 min after washout of Mn2+ as shown in (C). At each of the indicated points, 5-HT(30 µl of 2 mM) was injected into the superfusate.