Table 1.
Differentially expressed genes (fold change more than 1.5) between SMC and CO-treated SMC.
| Functional group Gene name |
Gene symbol | Different expression CO treatment vs. control |
|---|---|---|
| Cell proliferation and cell cycle | ||
| Heparin-binding EGF-like growth factor | HBEGF | DOWN |
| Cyclin-dependent kinase inhibitor 2A | CDKN2A | DOWN |
| Cyclin-dependent kinase 2 | CDK2 | DOWN |
| Myocyte enhancer factor 2 | MEF2 | UP |
| SHC transforming protein 1 | SHC1 | DOWN |
| Growth arrest-specific 1 | GAS1 | UP |
| Cell death and apoptosis | ||
| BCL2-antagonist/killer 1 | BAK1 | DOWN |
| Caspase 9, apoptosis-related cysteine peptidase | CASP9 | DOWN |
| Phosphoinositide-3-kinase | PI3K | UP |
| TNF receptor-associated factor 3 interacting protein 1 | TRAF3IP1 | DOWN |
| NF-κB signaling | ||
| Nerve growth factor | NGF | DOWN |
| Nerve growth factor receptor (TNFRSF16) associated protein 1 | NGFRAP1 | DOWN |
| BMP2 inducible kinase | BMP2K | DOWN |
| TNF receptor-associated factor 3 interacting protein 1 | TRAF3IP1 | DOWN |
| Phosphoinositide-3-kinase | PI3K | UP |
| Mitogen-activated protein kinase kinase kinase 3 | MEKK3 | DOWN |
| Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | NFKB2 | DOWN |