TABLE 1.

Properties of hippocampal pyramidal cells

	Electrophysiology
	Reg. spiking	Bursting	p value
RN (MΩ)	55.0 ± 3.1	33.7 ± 2.0	< 0.001
Sag ratio	0.84 ± 0.02	0.74 ± 0.02	< 0.001
Subthreshold dV/dt (mV/mS)	2.61 ± 0.53	4.39 ± 0.49	< 0.001
ADP amplitude (mV)	17.9 ± 1.3	22.2 ± 0.9	< 0.001
2nd spike threshold (mV)	−40.8 ± 0.7	−45.1 ± 0.9	< 0.001
Max 2nd falling dV/dt (mV/ms)	−56 ± 3	−65 ± 3	< 0.01
Max 2nd rising dV/dt (mV/ms)	240 ± 24	272 ± 22	< 0.05
1st spike FWHM (ms)	0.87 ± 0.01	0.82 ± 0.02	< 0.05
Resting membrane potential (mV)	−65.8 ± 0.7	−66.2 ± 0.4	n.s.
1st spike threshold (mV)	−53.1 ± 1.0	−52.4 ± 0.6	n.s.
Max 1st spike rising dV/dt (mV/ms)	460 ± 21	488 ± 21	n.s.
Max 1st spike falling dV/dt (mV/ms)	−106 ± 4	−113 ± 5	n.s.
2nd spike FWHM (ms)	1.18 ± 0.03	1.14 ± 0.04	n.s.
1st spike height (mV)	92.0 ± 1.5	90.3 ± 1.6	n.s.
2nd spike height (mV)	71.3 ± 3.0	70.0 ± 2.3	n.s.
AHP amplitude (mV)	−1.29 ± 0.25	−1.39 ± 0.31	n.s.
	Morphology
	Reg. spiking	Bursting	p value
Total tuft dendrite length (mm)	1.39 ± 0.02	1.49 ± 0.03	< 0.01
Total basal dendrite length (mm)	3.89 ± 0.26	3.08 ± 0.17	< 0.01
Basal branching order	4.40 ± 0.26	3.29 ± 0.23	< 0.01
Distance to main bifurcation (µm)	193.8 ± 19.3	264.4 ± 22.8	< 0.05
Basal branch points	50.1 ± 3.8	40.9 ± 3.1	< 0.05
Tuft branch points	33.7 ± 2.8	41.6 ± 3.3	< 0.05
Apical branching order	4.91 ± 0.72	7.93 ± 1.48	< 0.05
Proximal apical dendrite length (mm)	1.76 ± 0.21	1.35 ± 0.14	n.s.
Middle apical dendrite length (mm)	1.67 ± 0.28	1.48 ± 0.16	n.s.
Proximal apical branching order	5.53 ± 0.47	4.98 ± 0.36	n.s.
Middle apical branching order	4.81 ± 0.32	4.16 ± 0.40	n.s.
Proximal apical branch points	25.0 ± 3.4	28.0 ± 2.6	n.s.
Middle apical branch points	33.7 ± 1.9	34.6 ± 3.2	n.s.
Basal branches off soma	3.90 ± 0.47	3.65 ± 0.39	n.s.

Mean ± S.E.M. for all values. Electrophysiology, n = 268; Morphology, n = 110