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. 2012 Oct 24;13(11):13781–13803. doi: 10.3390/ijms131113781

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© 2012 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.

This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0).

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(a) Phenylephrine time-course dose response curve 24–168 h after control (n = 8 rats) or MWCNT inhalation (n = 7–9 rats). Values are mean ± SE. Time course evaluation does not reveal any significant differences between control and MWCNT exposed rats. (b) Responsiveness to phenylephrine of control (n = 8 rats) vs. MWCNT (24 h post-inhalation; n = 7 rats) coronary arteriolar smooth muscle. Values are mean ± SE. There are significant differences between control and rats exposed to MWCNT via inhalation after 24 h at the highest concentrations of PE.