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A proposed model for S-nitrosation of bSOD using GSNO as a nitrosating agent. The model assumes that bSOD unfolded at acidic pH and refolded at neutral pH. The numbers in parentheses represent the measured or estimated fractions of various possible bSOD species existing in the final reaction mixture. SH: unmodified Cys SH; SNO: S-nitrosated species; SSG: S-glutathiolated species.
