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Dose-Dependent Survival Benefit. The filled circles represent survival fraction (Number survivors/Number Infected) versus log dose (mg/kg) for Cynomolgus macaques infected with Marburg virus and treated with different doses of AVI-6003 (targeting VP24 and NP). The open circles represent the survival fraction versus log dose (mg/kg) for Rhesus macaques infected with Ebola virus and treated with AVI-6002 (targeting VP35 and VP24).
