Table 1.
Selected Phosphorodiamidate Morpholino Oligomers (PMO) Oligomers Evaluated for Ebola virus VP35, VP24, L and nucleoprotein (NP)
| Target | ID number | Sequence 5’ →3’ |
|---|---|---|
| EBOV-NP a | 0-1-0-1147 | CAG ATT TTC TGA GGA CGA GAA TC |
| EBOV-NP b | 0-1-0-1148 | CAT CCA GAT TTT CTG AGG AC |
| EBOV-NP c | 0-1-0-1149 | CTC GGC GCC ATC CAG ATT TTC |
| EBOV-NP d | 0-1-0-1150 | CAT ACT CGG AAT TTT GTG ATT C |
| EBOV-VP35 a | 0-1-63-413 | GTT GTC ATC TTG TTA GAC CAG C |
| EBOV-VP35 b | 0-1-63-539 | CCT GCC CTT TGT TCT AGT TG |
| EBOV-VP35 c | 0-1-0-1151 | CCT GCC CTT TGT TCT AGT TGT C |
| EBOV-VP24 a | 0-1-63-537 | GCC ATG GTT TTT TCT CAG G |
| EBOV-VP24 b | 0-1-0-1153 | TGT ATC GTC CCG TAG CTT TAG C |
| EBOV-VP24 c | NG-05-0165 | TTC AAC CTT GAA ACC TTG CG |
| EBOV-VP24 d | NG-05-364 | CAG TTC AAC CTT GAA ACC TTG CG |
| EBOV-L a | 0-1-63-538 | TGG GTA TGT TGT GTA GCC AT |
| EBOV-L b | 0-1-0-1157 | GTA TTG GGT ATG TTG TGT AGC |
| MARV-NP | NG-05-0174 | CCT AAC AAG CTA TGT AAA TC |
| MARV-VP35 | NG-05-0264 | TAT ATG ATG AGT CCC ACA TTG |
| MARV-VP24 | NG-05-0269 | CGT TGA TAA TTC TGC CAT G |