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Survival in Ebola virus Guinea Pig Lethal Challenge Model
| Target | PMO | PPMO | PMOplus | |||
|---|---|---|---|---|---|---|
| Dose (mg/kg) | Percent Fraction | Dose (mg/kg) | Percent Survival | Dose (mg/kg) | Percent Survival | |
| VP35 | 20 | 25 ± 12 (2) | - | - | 20 | 38 ± 00 (1) |
| VP24 | - | - | - | - | 20 | 49 ± 12 (2) |
| L | - | - | - | - | 20 | 13 ± 00 (1) |
| VP35 + VP24 | - | - | - | - | 20 | 83 ± 00 (1) |
| VP35 + VP24 + L | 20 | 46 ± 26 (4) | 1 | 12 ± 18 (2) | 20 | 33 ± 00 (1) |
| Control | - | 33 ± 47 (4) | - | 25 ± 35 (2) | - | 27 ± 18 (1) |
