Table 5.

Physical Characteristics of AVI-7357 for Ebola virus and AVI-7288 for Marburg virus.

	AVI-7537	AVI-7288
Sequence	GCC +ATG GT+T TT+T TC+T C+AG G	GAA TAT TAA C+AI +AC+T GAC +A+AG TC
Melting Temperature	81.0°C	84.2°C
Molecular Weight	6826 grams/mole	8179 grams/mole
Percent GC	47.4 %	30.4%
Target and Position	VP24 10330	NP 75
Association constant	9.97 X 107 M-1s-1	7.3 X106 M-1s-1
Dissociation constant	1.30 X 10-5 s-1	4.72 X10-5 s-1
Equilibrium Binding	1.30 X 10-13 M	6.47 X 10-12 M
EC50 (inhibit translation)	585 nM	872 nM