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. Author manuscript; available in PMC: 2012 Nov 29.
Published in final edited form as: Int J Radiat Biol. 2011 Nov;87(11):1126–1134. doi: 10.3109/09553002.2011.605418

Figure 1.

Figure 1

Time- and dose-dependent changes in IAUC induced by plinabulin in a C3H mammary carcinoma. DCE-MRI measurements were made pre- and post-treatment with either drug solvent or plinabulin and the post-treatment change relative to the pre-treatment estimate, determined. Top panel: Repeated measurements were made in the same animals receiving drug solvent (○) or 7.5 mg/kg plinabulin (●). Bottom panel: Measurements were made 3 hours after injecting different plinabulin doses. Results show mean values (±1 S.E.) from at least 6 animals. Asterisks indicate those values that are statistically different from controls.