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. Author manuscript; available in PMC: 2012 Nov 29.
Published in final edited form as: Int J Radiat Biol. 2011 Nov;87(11):1126–1134. doi: 10.3109/09553002.2011.605418

Figure 3.

Figure 3

The effect of plinabulin on tumour surviving fraction and the induction of necrosis in the KHT sarcoma. Top panel: Tumour surviving fraction was determined using the clonogenic survival assay 24 hours after injecting different doses of plinabulin. Middle panel: The degree of tumour necrosis was determined from histological sections 24 hours after injecting plinabulin. Bottom panel: Tumour surviving fraction was determined using the clonogenic survival assay 24 hours after local tumour irradiation with different radiation doses either given alone (○) or 1 hour prior to injecting the mice with 2.5 mg/kg plinabulin (●). Results show mean values (± 1 S.E.) from at least 3 animals. Asterisks indicate values statistically different from controls.