Fig. 3.

Correlation of CSF amyloid markers at baseline and follow-up. The Spearman correlation coefficient was used for analyses of correlations. Follow-up sample was the next collected consecutive sample after basal sample. Patients starting miglustat treatment (circles), patients on continuous treatment (triangles), and untreated patients (boxes). As previously reported, NPC patients treated with miglustat had lower CSF Aβ1-42, sAPP-α and sAPP-β, (Mattsson et al. 2011), but no effects of treatment start could be seen in this study