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Gelatinase activity is increased in MPS II. (a) Representative gelatine zymography in the serum of a patient with MPS III and age- and sex-matched controls (n = 10). (b) Quantitative analysis of gelatinolytic activity in serum of a patient with MPS II and healthy controls using a computer-supported image analysis program. Each bar represents the mean ± SED from zymographies, which were performed in triplicate for each patient
