Fig. 4.

Concentration of circulating MMP-2 (a), MMP-9 (b), TIMP-1 (c), TIMP-2 (d), in the serum of patients with MPS III (n = 5) and age- and sex-matched controls (n = 5, for each MPS III patient) measured by ELISA. Each bar represents mean ± SED from experiments performed in duplicate. Statistical significance: (*) p < 0.05