Table 1.

Acetoacetyl-CoA thiolase activities in the absence and presence of potassium ions

Fibroblasts	Acetoacetyl-CoA thiolase activity			SCOT activity
	−K+	+K+	+K+/−K+
Controls (n = 5)	5.0 ± 0.7	10.8 ± 0.9	2.2 ± 0.3	6.7 ± 2.1
GK69	3.6 ± 0.5	4.1 ± 0.9	1.2 ± 0.1	4.7 ± 1.4
GK77	4.2 ± 0.3	5.8 ± 1.5	1.4 ± 0.3	3.9 ± 0.5
T2D	4.5 ± 1.4	4.7 ± 1.6	1.0 ± 0.1	5.6 ± 0.5

Enzyme activity is expressed as nmol/min/mg of protein. In cases of patients, enzyme assay was done three times and shows average ± SD. T2D, A disease control