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. 2012 Nov 14;32(46):16331–16344. doi: 10.1523/JNEUROSCI.1577-12.2012

Table 1.

Drug effects on gamma frequency

Saline Nembutal (5 mg/kg) MK-801 (0.05 mg/kg)
56.5 51.9 57.3
p = 6 × 10−5 p = 0.12
Rat 9245 56.1 Hz 50.5 Hz 57.0 Hz
p = 3 × 10−8 p = 0.2
Rat 9244 56.7 Hz 52.5 Hz 58.0 Hz
p = 0.002
Rat 9233 56.8 Hz 52.7 Hz 57.0 Hz
p = 3 × 10−4 p = 0.9

Values are peak gamma frequencies, calculated by averaging across trials and 500 ms trial phases for each session and then averaging across sessions. p values are the results of t test comparisons of peak gamma frequency between drug and saline conditions. Top row shows means and p values across rats, and the bottom rows show means and p values within rats, across session. As a result of poor behavior in rat 9244, data collection under treatment with MK-801 was successfully obtained in only one session, so a within-rat comparison could not be made. Gamma frequency was consistently slower after administration of the barbiturate Nembutal (sodium pentobarbital), but gamma frequency after the NMDA antagonist MK-801 was not different from the saline condition.