Figure 2. Photograph of our experimental design.
Here a rat resides within in a Plexiglas box on top of a perforated aluminum plate. The holes in the plate allowed us to deliver ultrasound to the plantar aspect of the rat’s paws in a serial fashion, using our iFU device. That device consists of a transducer – characterized in Figure 1, covered by a water-filled cone to facilitate propagation of the ultrasound from the transducer into the rat’s paw, as well as to aid in the aiming of the iFU into the paw.