Table 4. Driver genes behind the asthma association on 17q21 and 2q12.
Chr | Genes | x | k | P = value |
17 | GSDMA | 7 | 130 | 0.0049 |
GSDMB | 4 | 94 | 0.054 | |
ORMDL3 | 3 | 204 | 0.2208 | |
2 | IL18R1 | 16 | 381 | 0.0004 |
IL18RAP | 0 | 0 | 1 | |
IL1RL1 | 19 | 283 | 1.88×10−07 |
m = Canonical list [27] (119 genes).
x = Canonical genes within the set of genes within 3 edges of QTL gene.
n = Bayesian – Canonical list (7000 genes).
k = Genes within 3 edges of QTL gene.