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. 2012 Nov 29;8(11):e1003054. doi: 10.1371/journal.pgen.1003054

Figure 5. ABI-1 mediates the lamellipodia-forming activity of MIG-10 in cultured HEK293 cells.

Figure 5

(A) Example of cell transfected with GFP and control shRNA. (B) Example of cell transfected with MIG-10::GFP and control shRNA. (C) Example of cell transfected with MIG-10::GFP and Abi1 shRNA. (D) Knockdown of Abi1 suppresses the lamellipodia-forming activity of MIG-10. Graph shows the average cell perimeter with lamellipodia. “Ctr.” means cells transfected with scrambled control shRNA. “−” means cells were not transfected with any shRNA. “Abi1” means cells were transfected with the PAV197 shRNA against Abi1. Error bars represent the standard error of the mean. *Bracket indicates statistically significant difference, t-test (p<0.0001). Scale bars are 5 µm.