Figure 1. GBV-C is associated with reduced CD4+ and CD8+ T cell activation in HIV-infected individuals.

The percentage of CD4+ (A) and CD8+ (B) T cells expressing CD38 and HLA-DR differed between GBV-C viremic (G+) subjects and those without GBV-C viremia (G-). Results of subjects not receiving combination antiretroviral therapy (HIV viremic; HV) or those with suppressed HIV RNA on therapy (HS) and statistical evaluation are provided.