Figure 4. Reference compound activity against T.b. brucei in the primary screening campaign.

Dose-response curves for the reference compounds pentamidine, puromycin and diminazene against T.b. brucei in the primary screening campaign. Means and standard deviations of replicate IC₅₀ values were (A) pentamidine, 14.7±4.7 nM (B) puromycin, 61.86±6.8 nM and (C) diminazene, 65.4 nM±12.5 nM. Data is representative of 13 control plates each containing 3 replicates of the compounds in dose, with batches indicative of daily screens.