Figure 7. Statistically-Significant Common Genomic Copy Number Aberrations among 22 FFPE Leiomyosarcomas.
Statistically significance of common aberrations was determined using the GISTIC algorithm. Commonly aberrant regions are plotted along the x-axis as a function of their chromosomal position and their q-values are plotted on the y-axis on a negative log10 scale so that the highest bars represent most significant genomic regions. Blue bars represent commonly amplified regions and red bars represent commonly deleted regions. Genomic regions with G-score >10 and q-values <0.05 are considered significant (shaded grey) and important candidate genes in these regions e.g. RB1, MYOCD are shown in black. Aberrations in individual samples were called using FASST2 Algorithm.