Table 2. Comparison of serum parameters of 8 months old female LH mutant and wild type mice after four months of high fat diet.
Wild type | LH mutant | p○ | |
Weight* | 40.5±6.2 | 43.8±4.4 | * |
Lipase∧ | 46.7±8.1 | 47.8±16.5 | ns |
Cholesterol# | 3.23±0.49 | 3.25±0.53 | ns |
HDL# | 1.45±0.15 | 1.44±0.16 | ns |
LDL# | 0.17±0.04 | 0.22±0.08 | ** |
Triglycerides# | 0.50±0.11 | 0.61±0.13 | ** |
FFA# | 1.14±0.12 | 1.16±0.11 | ns |
Glucose# | 9.97±1.77 | 11.5±1.83 | ** |
Insulin¤ | 3.1±1.1 | 4.4±2.3 | ns |
Adiponectin¤ | 17502±2048 | 10775±1226 | *** |
weight (g);
lipase (U/l);
cholesterol, HDL, LDL, triglycerides, FFA and glucose (mmol/l);
insulin and adiponectin (ng/ml) ± S.D. Wild type n = 18, LH mutant n = 25, except for insulin measurements wild type n = 13 and LH mutant n = 15.
P values were calculated using unpaired homoscedastic student t-test with two-tailed distribution.
p<0.05,
p<0.01,
p<0.001.
Abbreviations: HDL = High-density lipoprotein, LDL = Low-density lipoprotein, FFA = FreeFatty Acids.