Figure 3. Polymorphisms found in the LRR domain determine L5 and L6 recognition specificity.

A and C. Schematic diagrams of L6₅₉₂L5, L6₄₉₃L5 and L5₅₅₆L6 chimeric proteins. Domains from L6 are shaded white and domains from L5 are shaded grey. LRR units with polymorphic residues in the β-strand/β-turn structure (xxLxLxx motif) are marked with black bars. B and D. Growth of yeast strain HF7c expressing L6₅₉₂L5, L6₄₉₃L5 or L5₅₅₆L6 proteins fused to the GAL4 activation domain and wild-type (wt) and mutant AvrL567-A and -D proteins fused to the GAL4 DNA-binding domain. Cultures were grown on selective media lacking tryptophan, leucine and histidine and scored after 4 days.