Table 4. Polymorphisms showing significant association with wet AMD using multiple logistic regression.
Polymorphism | Genotypes compared | Stratum of subjects | OR | 95% CI | p value |
CFH rs1061170 | CC vs. TT+TC | C3: CC | 6.08 | 2.17–17.04 | 0.0006 |
CFH rs1061170 | CC vs. TT+TC | C3: CT+TT | 8.96 | 2.24–35.79 | 0.002 |
HTRA1 rs11200638 | TC+CC vs.TT | C3: CC | 45.04 | 5.30–382.83 | 0.0005 |
HTRA1 rs11200638 | TC vs. CC | C3: CT+TT | 4.34 | 1.09–17.28 | 0.04 |
Gas6 rs8191974 | GA+AA vs. GG | n.a. | 0.5 | 0.26–0.97 | 0.04 |
Stratum represents genotype of subjects involved in the analysis.